Jokes

25 Funny Ozempic Jokes That Cut Straight to Fun

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Jessica Amlee

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Ozempic first gained attention as a medication used to help manage type 2 diabetes, and it later became well known for its role in weight loss when prescribed by healthcare professionals. As more people started hearing about it, discussions quickly spread beyond doctors’ offices and into everyday conversations. It wasn’t long before Ozempic became one of those topics that seemed to be everywhere, making regular appearances in news stories, online posts, and casual chats.
As Ozempic continued to dominate conversations, it naturally found its way into internet humor. People began sharing funny comments, memes, and lighthearted takes on the topic, creating a whole collection of Ozempic jokes online. While the medication itself is a serious subject, the growing buzz around it gave people plenty of material for humor, adding a fun twist to an otherwise health-focused discussion.

Best Ozempic Jokes

Did you hear they developed a new snortable Ozempic?
It’s called Diet Coke.


To the guy who stole my Ozempic…
You’ll have nothing to gain.


Ozempic pills are very effective…
They drain your bank account so you don’t have money for food.


Did you hear about Big Pharma?
Thanks to Ozempic, Big Pharma is now ‘Medium Sized Pharma.’


Now that Lizzo is on Ozempic
…she’s only 80% that b*tch.


Forget Ozempic and Mounjaro. I’ve not long started a new diet.
The whisky diet. It’s great. I’ve lost two weeks already!


A blonde is overweight, so her doctor puts her on a diet and prescribes Ozempic.
“I want you to eat regularly for two days, then skip a day, and repeat the procedure for two weeks. The next time I see you, you’ll have lost at least five pounds.”
When the blonde returns, she’s lost nearly 20 pounds.
“Wow, that’s amazing!” the doctor says.
“Did you follow my instructions?”
The blonde nods…
“I’ll tell you, I’d thought I was going to drop dead that third day.”
“From hunger, you mean?” said the doctor.
“No, from skipping,” replied the blonde.


I invented a new chewing tobacco mixed with Ozempic.
I call it… skinny dip.


Did you hear about the man who was going to try Ozempic?
Then he remembered having diarrhea.


If people on keto are in ketosis,
Then people taking Ozempic must be in osmosis!


She set a record for rapid weight loss.
She even won a gold medal in the Ozempics.


I was so worried that Ozempic wouldn’t work for me.
But it’s taken a lot of weight off my shoulders!


Richard took way too much Ozempic.
What a waist.


Recommended: Fat Jokes


An obese guy wanted to lose weight, so he started taking Ozempic.
He also calls an agency and buys their “lose 5 pounds in 5 days” plan.
The next day, he finds a beautiful girl on his door saying, “If you catch me, I’m all yours”. He starts running after her, and after a few miles, he gives up. This same routine goes on for 5 days, and he sees that he has lost 5 pounds.
Impressed, he orders “lose 10 pounds in 5 days” from the agency and they reply, “Good sir! We are happy you are motivated, but this is gonna be tough!”. The guy says it’s no problem.
The next day, he finds an even more beautiful and hotter girl telling him to chase her and if he does, she’ll be all his, and so he runs after her for a few miles until he’s tired. This goes on for 5 days, and he realizes that he has lost 10 pounds.
Overjoyed, he again calls the agency and orders their “lose 25 pounds in 7 days” plan. The agency replies, “Are you sure, sir? I mean, this is our toughest plan out there…” to which the guy says, “Yes, sure! Between Ozempic and all this running, I’ve never been fitter in my life, so bring it on!”
The next day, he heard his doorbell ring. As he opened the door in the anticipation of a beautiful lady, he saw a huge naked man with a board around his neck:
“If I catch you, you’re all mine.”
The guy lost 30 pounds in those 7 days.


My girlfriend is on Ozempic.
I’m seeing less and less of her.


Easily lose weight by cutting these two things out of your diet instead of Ozempic:
Breakfast and dinner.


Body positivity left celebrities after Ozempic.
Turns out it couldn’t handle the weight of the situation.


Did you know America has outlawed Ozempic drugs?
They’re weapons of mass destruction


A woman at a diet club was lamenting the fact that she had put on weight despite taking Ozempic.
“I made my family’s favourite cake over the weekend,” she told the group, “and they ate half of it at dinner.
The next day, I kept staring at the other half until I finally weakened and cut myself a thin slice. Well, I’m ashamed to say that once I got the taste there was no stopping me. One slice led to another and soon the whole cake was gone. I was totally dismayed by my lack of willpower, and I knew that my husband would be bitterly disappointed in me.”
“What did he say when he found out?” asked the group leader gently.
“Oh, he never found out,” said the woman. “I made another cake and ate half!”


I take weight loss very seriously.
It’s not something I take lightly.


Yo mama is so fat, her weight loss program was featured on: Top 10 failed megaprojects.


Recommended: Fat Puns


Why was the successful weight loss doctor always frustrated?
Because his patients grew thin.


A guy goes into his doctor’s office and asks for some Ozempic pills for weight loss.
The doctor gives him two hundred tiny white pills in a bottle and writes on a small sheet of paper the words “Three times a day”.
The guy asks, “How many do I take?”
The doctor says, “You don’t take them. Three times a day, I want you to spill the whole bottle on the floor and pick them up one by one.”


Do you have a funnier Ozempic joke? Write down your best jokes in the comment section below!

Jessica Amlee, born in 1996 in Laughlin, Nevada, is a delightful humorist and joke writer with a penchant for puns. She studied at Emerson College, earning a Bachelor of Fine Arts in Comedy. Jessica's comedic style combines snappy one-liners and observational humor, making her a rising star in the world of comedy.

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