The Khopdi Tod Saale Ka meme originates from the Bollywood movie Hera Pheri released in the year 2000. In the comedy movie, Baburao(the character played by Paresh Rawal) says these lines to Shyam(the character played by Sunil Shetty) when Raju(the character played by Akshay Kumar) mistakenly hits him with a raw coconut. The popular use of Khopdi Phod Saale Ka meme is to express the feeling of disgust towards someone.