The Zindagi Ho To Aisi Ho meme originates from the 2018 Excel Entertainment’s Web series Mirzapur Season 1. In this Amazon Prime Video series episode, Guddu Bhaiya (the character played by Ali Fazal) says this to Bablu Bhaiya (the character played by Vikrant Massey) when he is mesmerized by the lifestyle of Munna Bhaiya. The popular use of Zindagi Ho To Aisi Ho meme is to admire someone’s luck.
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